
1) Area of great society concern 2) Eastern US region 3) Geographic area 4) Geographic region 5) Geographical area 6) Geographical region 7) Part of western Maryland
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https://www.crosswordclues.com/clue/appalachia

Appalachia is a cultural region in the Eastern United States that stretches from the Southern Tier of New York to northern Alabama, Mississippi, and Georgia. While the Appalachian Mountains stretch from Belle Isle in Canada to Cheaha Mountain in Alabama, the cultural region of Appalachia typically refers only to the central and southern portions o...
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http://en.wikipedia.org/wiki/Appalachia
[Mesozoic] In the Mesozoic Era Appalachia was an island land mass separated from Laramidia to the west by the Western Interior Seaway. The seaway eventually shrank, divided across the Dakotas, and retreated towards the Gulf of Mexico and Hudson Bay. This left the island masses joined in the continent of North America as the Rocky Mountains ...
Found on
http://en.wikipedia.org/wiki/Appalachia_(Mesozoic)

Appalachia Indians in Eastern U.S.
Found on
http://users.michweb.net/~orendon/americans/glosary2.html

[
n] - an impoverished coal mining area in the Appalachian Mountains (from Pennsylvania to North Carolina)
Found on
http://www.webdictionary.co.uk/definition.php?query=Appalachia
noun an impoverished coal mining area in the Appalachian Mountains (from Pennsylvania to North Carolina)
Found on
https://www.encyclo.co.uk/local/20974

a Paleozoic landmass, the erosion of which provided the sediments to form the rocks of the Appalachian Mountains. · a region in the E United States, in the area of the S Appalachian Mountains, usually including NE Alabama, NW Georgia, NW South Carolina, E Tennessee, W Virginia, E Kentucky, West Virginia, and SW Pennsylvania.
Found on
https://www.infoplease.com/dictionary/appalachia
No exact match found.