Copy of `Superglossary - Genetics`
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Superglossary - Genetics
Category: Sciences > Genetics
Date & country: 11/12/2013, USA Words: 460
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Cytological BandAn area of the chromosome that stains differently from areas around it.
Cytological MapA type of chromosome map whereby genes are located on the basis of cytological findings obtained wit
Cytoplasmic TraitA genetic characteristic in which the genes are found outside the nucleus, in chloroplasts or mitoch
Cytosine (C)A nitrogenous base, one member of the base pair gc (guanine and cytosine) in dna.
Data WarehouseA collection of databases, data tables, and mechanisms to access the data on a single subject.
Degenerate CodonA codon that specifies the same amino acid as another codon.
DeletionThe loss of a segment of the genetic material from a chromosome.
Deletion MapA description of a specific chromosome that uses defined mutations --specific deleted areas in the g
Deletion MappingThe use of overlapping deletions to localize the position of an unknown gene on a chromosome or link
Deoxyribonucleic Acid (DNA)The molecule that encodes genetic information. Dna is a double-stranded molecule held together by we
DeoxyriboseA type of sugar that is one component of dna (deoxyribonucleic acid).
DiploidA full set of genetic material, consisting of paired chromosomes one chromosome from each parental s
Directed EvolutionA laboratory process used on isolated molecules or microbes to cause mutations and identify subseque
Directed MutagenesisAlteration of dna at a specific site and its reinsertion into an organism to study any effects of th
Directed SequencingSuccessively sequencing dna from adjacent stretches of chromosome.
DiseaseAny deviation from the normal structure or function of any part, organ, or system of the body that i
Disease-Associated GenesAlleles carrying particular dna sequences associated with the presence of disease.
DmdDuchenne muscular dystrophy.
DNA BankA service that stores dna extracted from blood samples or other human tissue.
DNA Fingerprint TechniqueA method employed to determine differences in amino acid sequences between related proteins
DNA HybridizationA technique for selectively binding specific segments of single-stranded (ss) dna or rna by base pai
DNA ProbeAny biochemical used to identify or isolate a gene, a gene product, or a protein.
DNA Repair GenesGenes encoding proteins that correct errors in dna sequencing.
DNA ReplicationThe use of existing dna as a template for the synthesis of new dna strands. In humans and other euka
DNA SequenceThe relative order of base pairs, whether in a fragment of dna, a gene, a chromosome, or an entire g
DNA SequencingPlus and minus or 'primed synthesis' method, developed by sanger, dna is synthesized in vitro in suc
DomainA discrete portion of a protein with its own function. The combination of domains in a single protei
DominantAlleles that determine the phenotype displayed in a heterozygote with another (recessive) allele.
Double HelixThe twisted-ladder shape that two linear strands of dna assume when complementary nucleotides on opp
Down SyndromeA type of mental deficiency due to trisomy (three copies) of autosome 21, a translocation of 21 or m
Draft SequenceThe sequence generated by the hgp as of june 2000 that, while incomplete, offers a virtual road map
Duchenne-Becker Muscular DystrophyThe most common and severe form of muscular dystrophy
DwarfismConditions of short stature with adult height under 4'10' as adult, usually with normal intelligence
DystoniaNeurologic condition involving repeated twisting and movement. Involves a variety of muscle groups.
ElectrophoresisA method of separating large molecules (such as dna fragments or proteins) from a mixture of similar
ElectroporationA process using high-voltage current to make cell membranes permeable to allow the introduction of n
Embryonic Stem (ES) CellsAn embryonic cell that can replicate indefinitely, transform into other types of cells, and serve as
EndonucleaseAn enzyme that cleaves its nucleic acid substrate at internal sites in the nucleotide sequence.
Endonuclease Restriction EnzymeA protein that recognizes specific, short nucleotide sequences and cuts dna at those sites. Bacteria
EnzymeA protein that acts as a catalyst, speeding the rate at which a biochemical reaction proceeds but no
EpistasisOne gene interfers with or prevents the expression of another gene located at a different locus.
ErythrocytesThe hemoglobin-containing cell found in the blood of vertebrates.
Escherichia ColiCommon bacterium that has been studied intensively by geneticists because of its small genome size,
EthicsThe study of fundamental principles which defines values and determines moral duty and obligation.
EuchromatinThe chromatin that shows the staining behavior characteristic of the majority of the chromosomal com
EugenicsThe improvement of humanity by altering its genetic composition by encouraging breeding of those pre
EukaryoteCell or organism with membrane- bound, structurally discrete nucleus and other well- developed subce
EukaryoteCell or organism with membrane-bound, structurally discrete nucleus and other well-developed subcell
Exogenous DNADna originating outside an organism that has been introducted into the organism.
ExonsPortion of a gene included in the transcript of a gene and survives processing of the rna in the cel
ExonucleaseAn enzyme that cleaves nucleotides sequentially from free ends of a linear nucleic acid substrate.
Expressed Sequence Tag (EST)A short strand of dna that is a part of a cdna molecule and can act as identifier of a gene. Used in
Fetal Alcohol SyndromeA link between excessive alcohol consumption during pregnancy and birth defects
Filial Generation (F1-F2)Each generation of offspring in a breeding program, designated f1, f2, etc.
FingerprintingIn genetics, the identification of multiple specific alleles on a person's dna to produce a unique i
Finished DNA SequenceHigh-quality, low error, gap-free dna sequence of the human genome. Achieving this ultimate 2003 hgp
Flow CytometryAnalysis of biological material by detection of the light- absorbing or fluorescing properties of ce
Flow KaryotypingUse of flow cytometry to analyze and separate chromosomes according to their dna content.
ForensicsThe use of dna for identification. Some examples of dna use are to establish paternity in child supp
Fragile SitesA non-staining gap of variable width that usually involves both chromatids and is always at exactly
Fragile-X SyndromeX-linked trait
Fraternal TwinSiblings born at the same time as the result of fertilization of two ova by two sperm. They share th
Full Gene SequenceThe complete order of bases in a gene. This order determines which protein a gene will produce.
Functional GenomicsThe study of genes, their resulting proteins, and the role played by the proteins the body's biochem
GameteAn haploid cell.gel electrophoresis the process by which nucleic acids (dna or rna) or proteins are
GC-Rich AreaMany dna sequences carry long stretches of repeated g and c which often indicate a gene-rich region.
GeneThe fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotid
Gene AmplificationAny process by which specific dna sequences are replicated disproportionately greater than their rep
Gene Chip TechnologyDevelopment of cdna microarrays from a large number of genes. Used to monitor and measure changes in
Gene ExpressionThe process by which a gene's coded information is converted into the structures present and operati
Gene FamilyGroup of closely related genes that make similar products.
Gene MapThe linear arrangement of mutable sites on a chromosome as deduced from genetic recombination experi
Gene MappingDetermination of the relative positions of genes on a dna molecule (chromosome or plasmid) and of th
Gene PoolAll the variations of genes in a species.
Gene PredictionPredictions of possible genes made by a computer program based on how well a stretch of dna sequence
Gene ProductThe biochemical material, either rna or protein, resulting from expression of a gene. The amount of
Gene TherapyAn experimental procedure aimed at replacing, manipulating, or supplementing nonfunctional or misfun
Gene TransferIncorporation of new dna into and organism's cells, usually by a vector such as a modified virus. Us
Genetic CodeThe sequence of nucleotides, coded in triplets (codons) along the mrna, that determines the sequence
Genetic CounselingThe educational process that helps individuals, couples, or families to understand genetic informati
Genetic DiscriminationPrejudice against those who have or are likely to develop an inherited disorder.
Genetic EngineeringAltering the genetic material of cells or organisms to enable them to make new substances or perform
Genetic IllnessSickness, physical disability, or other disorder resulting from the inheritance of one or more delet
Genetic Linkage MapA chromosome map showing the relative positions of the known genes on the chromosomes of a given spe
Genetic MarkerA gene or other identifiable portion of dna whose inheritance can be followed.
Genetic MosaicAn organism in which different cells contain different genetic sequence. This can be the result of a
Genetic PolymorphismDifference in dna sequence among individuals, groups, or populations (e.g., genes for blue eyes vers
Genetic PredispositionSusceptibility to a genetic disease. May or may not result in actual development of the disease.
Genetic ScreeningTesting groups of individuals to identify defective genes capable of causing hereditary conditions.
Genetic TestingAnalyzing an individual's genetic material to determine predisposition to a particular health condit
Genetic VariationA phenotypic variance of a trait in a population attributed to genetic heterogeneity.
GeneticsThe study of the patterns of inheritance of specific traits.
GenomeAll of the genes carried by a single gamete
Genome ProjectResearch and technology-development effort aimed at mapping and sequencing the genome of human being
Genomic LibraryA collection of clones made from a set of randomly generated overlapping dna fragments representing
GenomicsThe study of genes and their function.
GenotypeThe genetic constitution of an organism, as distinguished from its physical appearance (its phenotyp
Germ CellA sex cell or gamete (egg or spermatozoan).haldane equation haldane's law
Germ LineThe continuation of a set of genetic information from one generation to the next.
Germ Line Gene TherapyAn experimental process of inserting genes into germ cells or fertilized eggs to cause a genetic cha