HGD: The gene encoding an enzyme called homogentisate 1,2-dioxygenase (also known as homogentisate oxidase). HGD is located on chromosome 3 in region 3q21-q23. Homogentisate oxidase is active chiefly in the liver and kidneys. It is needed to break down the amino acids phenylalanine and tyrosine. Previous steps convert these two amino acids into a m...
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