Dyshidrotic eczema: Irritation of the skin on the palms of hands and soles of the feet characterized by clear, deep blisters that itch and burn. Common Misspellings: dyshidrotic excema, dyshidrotic exzema, dyshidrotic exema, dyshidrotic ecxema, dyshidrotic ecsema Found on http://www.medterms.com/script/main/art.asp?articlekey=9635