Copy of `NMS - Chemical and biological services terms`

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NMS - Chemical and biological services terms
Category: Sciences > Analysis
Date & country: 11/12/2007, UK
Words: 25


Accreditation
Third-party statement based on a decision following review that competence to carry out a task has been demonstrated.

Accuracy
Closeness of agreement between a single test result or measurement result and the true value.

Analyte
Any substance whose identity or concentration is to be determined.

Bias
The difference between the mean value of a set of test results or measurement results and the true value.

Calibration
Operation that establishes the relation, obtained by reference to one or more measurement standards, between the response of an instrument and the values of the standards.

Certification
Third-party statement based on a decision following review that fulfilment of specified requirements have been demonstrated. Usually related to products, processes, systems or persons.

Certified reference material (CRM)
A reference material characterized by a metrologically valid procedure for one or more specified properties, accompanied by a certificate that states the value of the specified property, its associated uncertainty, and a statement of metrological traceability.

Control charts
Routine charting of data obtained from the analysis of quality control materials to check that the results lie within predetermined limits.

Error
The difference between a result of a measurement and the true value of the measurand.

Fitness for purpose
A formal process of assessing that a method is suitable for a given application.

Good Laboratory Practice
A world-wide quality management system for the design, conduct and reporting of studies in support of licensing/ product registration of drugs/food/chemicals for human or veterinary use. Registration to this system is frequently mandatory for work of this nature.

Limit of detection
The lowest amount of an analyte that can be measured with reasonable statistical certainty.

Measurand
A particular quantity subject to measurement.

Measurement uncertainty
A range of values within which the true value of the measurement is expected to lie with a given level of confidence.

Precision
The closeness of agreement between independent test results obtained under stipulated conditions. A precision estimate is a statistical measure of the spread of the results obtained from a series of replicate measurements.

Proficiency Testing
Determination of laboratory testing performance by means of interlaboratory comparisons.

Quality Assurance
Part of quality management focused on providing confidence that quality requirements will be fulfilled. It is all the activities undertaken by an organisation to ensure a defined standard of quality for its goods or services.

Quality control
Part of quality management focused on fulfilling quality requirements.

Quality control chart
Routine charting of data obtained from the analysis of quality control materials to check that the results lie within predetermined limits.

Quality control sample (material)
A material that is fully characterized in-house or by a third party, similar in composition to the types of samples normally examined, stable, homogeneous and available in large quantities so that it can be used over a long period of time for monitoring method performance..

Reference Material
A Material, sufficiently homogeneous and stable with respect to one or more properties, which has been established to be fit for its intended purpose.

Standard operating procedure
A documented set of instructions for an analytical method that completely specifies how to operate the method. It includes a statement of the scope of the method, what apparatus and chemicals are to be used, and how the reported result is to be calculated and expressed.

Trace analysis
Analysis of samples containing a low concentration of the anlayte(s) of interest – typically less than 100 mg kg-1. Note that trace analysis is also used to describe the analysis of a very small quantity of sample material (especially in forensic analysis).

Traceability
A property of the result of a measurement or the value of a standard whereby it can be related to stated references, usually national or international standards, through an unbroken chain of comparisons all having stated uncertainties.

Validation
Confirmation by examination and provision of objective evidence that the particular requirements for a specified intended use are fulfilled.