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Look up: HGPRT

  1. HGPRT
    (= hypoxanthine-guanine phosphoribosyl transferase) Enzyme that catalyses the first step in the pathway for salvage of the purines hypoxanthine and guanine. The phosphoribosyl moiety is transferred from an activated precursor, 5-phosphoribosyl 1-pyrophosphate. Since animal cells can synthesize purines de novo , HGPRT-mutants can be selected by their resistance to toxic purine analogues. A genetic lesion in HGPRT in humans underlies the Lesch-Nyhan syndrome. See HAT medium.
    Found on http://www.encyclo.co.uk/visitor-contrib

  2. HGPRT
    Synonym for hypoxanthine-guanine phosphoribosyl transferase ... <enzyme> An enzyme which plays an important role in the making of ATP and GTP from guanine -- the only way guanine, adenine, or other purine molecules are able to become part of nucleic acids. Biologists study gene action via the ...
    Found on http://www.mondofacto.com/facts/dictiona

  3. HGPRT
    Type: Abbreviation Definitions: 1. Abbreviation for hypoxanthine guanine phosphoribosyltransferase.
    Found on http://www.medilexicon.com/medicaldictio

...

12 February 2012

This day in history:
/calendar/ On February 12, 1809, Charles Robert Darwin was born at The Mount in Shrewsbury, Shropshire, England. Darwin was one of the last of the eclectic scientists who preceded the age of professional specialization. His genius lay in his ability to select, from the facts which he so diligently collected, every relevant point and fit it into his bold and far-reaching theories. He was not the first to advance a theory of evolution; but his massive weight of evidence carried conviction where earlier theorists had failed. He was shy and modest and shrank from controversy, an unfortunate trait in the author of the most controversial book of the century. read more

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