(= large fibroblast glycoprotein; chondroitin sulphate core protein) Protein (264 kD) involved in cell signalling. N-terminal region similar to glial hyaluronic acid binding protein, centre has glycosaminoglycan attachment sites, C-terminal region has EGF-like repeats.


Versican, also known as VCAN, is a large extracellular matrix proteoglycan that is present in a variety of human tissues. It is encoded by the VCAN gene. Versican is a large chondroitin sulfate proteoglycan with an apparent molecular mass of more than 1000kDa. In 1989, Zimmermann and Ruoslahti cloned and sequenced the core protein of fibroblast ch...
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