A protein (8.5 kD) found in all eukaryotic cells. Can be linked to the lysine side chains of proteins by formation of an amide bond to its C-terminal glycine in an ATP-requiring process. The protein/ubiquitin complex is subject to rapid proteolysis. Ubiquitin also has a role in the heat-shock response.
Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. It was discovered in 1975 by Goldstein and further characterized throughout the 1970s and 1980s. There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A. Ubiquitination is a post-tr...Found on http://en.wikipedia.org/wiki/Ubiquitin
(from the article `Ciechanover, Aaron J.`) ...that they discovered involves a series of carefully orchestrated steps by which cells degrade, or destroy, the proteins that no longer serve any ... ...Philadelphia. There the three scientists did much of their prizewinnning research on how cells degrade, or destoy, the proteins that are no ...Found on http://www.britannica.com/eb/a-z/u/1
<protein> A protein (8.5 kD) found in all eukaryotic cells. Can be linked to the lysine side chains of proteins by formation of an amide bond to its C terminal glycine in an ATP requiring process. ... The protein/ubiquitin complex is subject to rapid proteolysis. Ubiquitin also has a role in the heat shock response. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: ū-bik′kwi-tin Definitions: 1. A small (76 amino acyl residues) protein found in all cells of higher organisms and one with a structure that has changed minimally during evolutionary history; involved in at least two processes; histone modification and intracellular protein breakdown.Found on http://www.medilexicon.com/medicaldictionary.php?t=95378
ubiquitin A small protein, present in all eukaryotic cells, that participates in the destruction of defective proteins and in the synthesis of new proteins.Found on http://www.wordinfo.info/words/index/info/view_unit/2210/2
Ubiquitin: A small but extremely important protein that acts the 'kiss of death' to other proteins. Ubiquitin consists of only 76 amino acids. In the normal course of events, proteins are inactivated by the attachment of ubiquitin to them, a process called ubiquitination. Ubiquitin acts as a tag by which the protein-transport machinery ferries a pr...Found on http://www.medterms.com/script/main/art.asp?articlekey=26110
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