Major structural protein of inner root sheath cells and medulla of hair follicle, present in small amounts in other specialised epithelia. Trichohyalin is a high molecular weight alpha-helix-rich protein that forms rigid structures as a result of postsynthetic modification by transglutaminases that cross-link the proteins and peptidyl-arginine deiminase that converts arginine to citrulline and modifies structure of the protein. Modified trichohyalin is thought to serve as a keratin intermediate filament-associated matrix protein, like filaggrin.
A substance of the nature of keratohyalin found in the developing inner root sheath of the hair follicle. ... (05 Mar 2000) ... Found on http://www.encyclo.co.uk/local/20973
trichohyalin 1. A substance of the nature of keratohyalin (colorless-translucent protein) found in the developing inner root sheath of the hair follicle. 2. The hyaline (clear, translucent, and containing no fibers or granular material) of the hair.Found on http://www.wordinfo.info/words/index/info/view_unit/2179/8
Type: Term Pronunciation: trik′ō-hī′ă-lin Definitions: 1. A substance of the nature of keratohyalin found in the developing inner root sheath of the hair follicle.Found on http://www.medilexicon.com/medicaldictionary.php?t=93781
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