Rabaptin-5 (117 kD) interacts with rab5-GTP and is essential for rab-mediated endosomal fusion. Both ends of rabaptin have coiled-coil domains characteristic of vesicular transport proteins.


Rabaptin is a key protein involved in regeneration of injured axons. Regeneration of injured axons at neuromuscular junctions is regulated by extra-cellular protein factors that promote neurite outgrowth. A novel neurite outgrowth factor from chick denervated skeletal muscle has been cloned and characterised. The protein, termed neurocrescin (raba...
Found on http://en.wikipedia.org/wiki/Rabaptin
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