Pregnanolone (3α-hydroxy-5β-pregnan-20-one or 3α,5β-tetrahydroprogesterone; sometimes abbreviated as 3α,5β-THP), also known as eltanolone (INN), is an endogenous neurosteroid that is synthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, and is known to have sedative, anxiolytic, and anticonvulsant effect...
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<chemical> A pregnane found in the urine of pregnant women and sows. It has anaesthetic, hypnotic, and sedative properties. ... Chemical name: Pregnan-20-one, 3-hydroxy-, (3alpha,5beta)- ... (12 Dec 1998) ...
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