(= FK506 binding protein) A family of small intracellular proteins (around 11 kD) that bind the immunosuppressive drug FK506 (tacrolimus), thus are immunophilins. Like cyclophilin have peptidyl-prolyl isomerase activity but are not structurally similar.
FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence. FKBPs have been identified in many eukaryotes from yeast to humans and function as protein folding chaperones for proteins containing proline residues. Along with cyclophili...Found on http://en.wikipedia.org/wiki/FKBP
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