(= CD105) Homodimeric glycoprotein (180 kD) with TGF- binding activity, expressed on endothelial cells and pre-B cells.
Type: Term Pronunciation: en′dō-glin Definitions: 1. A protein on the surface of endothelial cells that binds to transforming growth factor-β.Found on http://www.medilexicon.com/medicaldictionary.php?t=29106
Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations ...Found on http://en.wikipedia.org/wiki/Endoglin
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