dactinomycin

<chemical> An antitumour antibiotic derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. ... Pharmacological action: ant...
Found on http://www.encyclo.co.uk/local/20973

dactinomycin

(dak″tĭ-no-miĀ“sin) an antitumor antibiotic of the actinomycin complex (actinomycin D), produced by Streptomyces parvulus. Used to treat rhabdomyosarcoma and Wilms tumor in children, as well as Ewing sarcoma, Kaposi sarcoma, osteogenic sarcoma, soft tissue sarcomas, testicular carcinoma, and choriocarcinoma.
Found on http://www.encyclo.co.uk/local/21001

dactinomycin

(from the article `drug`) Antineoplastic antibiotics (doxorubicin, daunorubicin, bleomycin, mitomycin, and dactinomycin) are derived from Streptomyces species. While they may ...
Found on http://www.britannica.com/eb/a-z/d/1

dactinomycin

Type: Term Pronunciation: dak′ti-nō-mī′sin Definitions: 1. An antineoplastic antibiotic produced by several species of Streptomyces (S. parvulus). Synonyms: actinomycin D
Found on http://www.medilexicon.com/medicaldictionary.php?t=22796

Dactinomycin

Dactinomycin is a polypetipe isolated from the bacterium Streptomyces parvullus and used in the treatment of cancer as a cytotoxin.
Found on http://www.probertencyclopaedia.com/browse/ED.HTM

Dactinomycin

A medication that is commonly prescribed to treat malignant tumors, including choriocarcinoma. Intrauterine exposure to the drug has been associated with an increased risk of stillbirth and low-birth weight in the infant.
Found on http://www.pregnology.com/AZ/D/1

dactinomycin

An anticancer drug that is a type of antitumor antibiotic.
Found on http://www.cancer.gov/dictionary?expand=D

Dactinomycin

Dactinomycin (INN, BAN, AAN and USAN also known generically as actinomycin D), is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. As one of the older chemotherapy drugs, it has been used for many years. == History == Actinomycin D was the first antibi...
Found on http://en.wikipedia.org/wiki/Dactinomycin
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