aggrecanase

Type: Term Pronunciation: ag-gre′ka-nāz Definitions: 1. An enzyme found in cartilage that degrades extracellular matrix, especially cartilage.
Found on http://www.medilexicon.com/medicaldictionary.php?t=1758

aggrecanase

<enzyme> Cleaves aggrecan from articular cartilage predominantly between glu-373 and ala-374; activity found in bovine articular cartilage, bovine growth plate and chondrocyte monolayer cultures ... Registry number: EC 3.4.99.- ... (26 Jun 1999) ...
Found on http://www.encyclo.co.uk/local/20973

Aggrecanase

Aggrecanases are proteolytic enzymes that are members of the ADAM protein (A Disintegrin And Metalloprotease) family. Aggrecanases act on large proteoglycans known as aggrecans, which are components of connective tissues such as cartilage. The inappropriate activity of aggrecanase is a mechanism by which cartilage degradation occurs in diseases su...
Found on http://en.wikipedia.org/wiki/Aggrecanase
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