Type: Term Pronunciation: nī′kas-trin Definitions: 1. Transmembrane glycoprotein involved in presenilin complex activities.
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Nicastrin, also known as NCSTN, is a protein that in humans is encoded by the NCSTN gene. Nicastrin (abbreviated NCT) is a protein that is part of the gamma secretase protein complex, which is one of the proteases involved in processing amyloid precursor protein (APP) to the short Alzheimer`s disease-associated peptide amyloid beta. The other pro....
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