Plasma serine proteases normally present as inactive prekallikreins which are activated by Hagemann factor. Act on kininogens to produce kinins. Contain an apple domain.
Kallikreins are a subgroup of serine proteases, enzymes capable of cleaving peptide bonds in proteins. In humans, plasma kallikrein (KLKB1) has no known homologue, while tissue kallikrein-related peptidases (KLKs) encode a family of fifteen closely related serine proteases. These genes are localised to chromosome 19q13, forming the largest contigu...Found on http://en.wikipedia.org/wiki/Kallikrein
(from the article `renal system`) Another substance that causes the dilation of blood vessels, the enzyme kallikrein, may also exert an influence on renal blood flow. Kallikrein is ...Found on http://www.britannica.com/eb/a-z/k/5
(kal″ĭ-kre´in) any of several serine endopeptidases that cleave kininogens to form kinins. plasma kallikrein a hydrolytic enzyme of the plasma that cleaves HMW (high-molecular-weight) kininogen to produce bradykinin. It also activates several blood coagulation factors and plasm...Found on http://www.encyclo.co.uk/local/21001
<protein> Plasma serine proteases normally present as inactive prekallikreins which are activated by Hageman factor. Act on kininogens to produce kinins. Contain an apple domain. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: kal′i-krē′in Definitions: 1. A group of enzymes (plasma, tissue, pancreatic, urinary, or submandibular kallikrein) that converts kininogen by proteolysis to bradykinin or kallidin. Trypsin and plasmin can also effect the conversion. Plasma kallikrein activates factor XII and acts on kininogen. Tissue kalli...Found on http://www.medilexicon.com/medicaldictionary.php?t=46646
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