(= cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) Hereditary adult-onset condition causing stroke and dementia, mapped to Chr 19 and thought to be a defect in Notch > Notch-3, though how a defect in this signalling pathway leads to the pathological effect remains unclear.
CADASIL: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. An inherited form of vascular dementia that strikes relatively young adults of both sexes and is characterized by multiple strokes, dementia, migraine-like headaches, and psychiatric disturbances. CADASIL is due to mutation of a gene called NOTCH3 l...Found on http://www.medterms.com/script/main/art.asp?articlekey=21886
Cerebral Autosomal Dominant Arteriopathy with Sub cortical Infarcts and LeukoencephalopathyFound on http://dementia.ie/information/glossary1
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathyFound on http://www.translationdirectory.com/glossaries/glossary124.htm
No exact match found