Back-fusion is the fusion of internal (intraluminal) vesicles within multivesicular bodies or late endosomes with the endosome’s limiting membrane. The process is believed to be mediated by lysobiphosphatidic acid (LBPA), phosphatidylinositol-3-phosphate, Alix, and an apparent dependence on an acidic pH. MHC class 2 and other proteins (CD63 and ...
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