Astacin, a zinc-endopeptidase from crayfish ( Astacus ), is the prototype for the astacin family of metallo-endopeptidases. Family includes BMP-1, Meprin A, stromelysin 1, and thermolysin.


In molecular biology, astacin is a family of metallopeptidases. These metallopeptidases belong to the MEROPS peptidase family M12, subfamily M12A (astacin family, clan MA(M)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA and the predicted active site residues for me...
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