APC (gene)

APC (gene): A major gene that is involved in causing colorectal cancer. APC is involved in both sporadic and familial forms of colorectal cancer. A mutation in the APC gene is the earliest detectable molecular abnormality in colorectal cancer. This mutation imitates the neoplastic process 20 to 30 years before the malignancy itself is full-blown. A...
Found on http://www.medterms.com/script/main/art.asp?articlekey=38758
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