AKAP79

(= A kinase anchoring protein) Scaffold protein from mammalian cells to which Protein Kinase A (PKA), calcineurin and Protein Kinase C(PKC) all bind. PKC apparently binds at a different site so that PKC and calcineurin can, for example, simultaneously be bound. Through anchorage to AKAP79, kinases and phosphatases are co-localised at postsynaptic densities in neurons. AKAP79 resembles yeast STE5. ...
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