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(a-tip´e-ә) deviation from the normal or typical state.
(a-tip´ĭ-kәl) irregular; not conformable to the type.
(ә-trak´shәn) the force or influence by which one object is drawn toward another. capillary attraction the force that causes a liquid to rise in a fine-caliber tube.
(ә-trish´әn) the wearing away of a substance or structure (such as the teeth) in the course of normal use.
the most common form of familial amyloidosis, in which any of numerous mutations of the gene encoding transthyretin cause systemic autosomal dominant disorders characterized by polyneuropathies, cardiomyopathies, and variable organ involvement. See also familial amyloid polyneuropathy.
(at´ĭ-tldbomacd) a posture or position of the body; in obstetrics, the relation of the various parts of the fetal body to one another. a pattern of mental views established by cumulative prior experience.
those reflexes having to do with the position of the body, primarily controlled by input from receptors in the utriculus; called also statotonic reflexes.
(at″ĭ-kot´ә-me) incision into the epitympanic recess (attic).
(at″ĭ-ko-an-trot´ә-me) surgical exposure of the epitympanic recess (attic) and mastoid antrum.
(at´ik) a small upper space of the middle ear, containing the head of the malleus and the body of the incus.
(ә-ten″u-a´shәn) the act of thinning or weakening. the change in the virulence of a pathogenic microorganism induced by passage through another host species, decreasing its virulence for the native host and increasing it for the new host. This is the basis for the development of live vacc...
one whose pathogenicity has been reduced by serial animal passage or other means.
attenuated viral vaccine
attenuated virus vaccine modified live virus vaccine.
a vaccine prepared from live microorganisms or viruses cultured under adverse conditions, leading to loss of their virulence but retention of their ability to induce protective immunity.
attention reflex of pupil
alteration of size in the pupil when the attention is suddenly fixed; called also Piltz reflex.
a childhood mental disorder characterized by inattention behaviors such as distractibility, forgetfulness, not finishing tasks, and not appearing to listen; hyperactivity; and impulsive behaviors such as fidgeting or squirming, difficulty remaining seated, excessive running or climbing, feelings of restlessness, difficult...
(ә-ten´ding) attending physician. being or pertaining to such a physician.
(at″ә-pul´jīt) a clay mineral that contains aluminum silicate and is the main ingredient of fuller's earth; activated attapulgite is a heat-treated form that is administered orally in the treatment of diarrhea.
in analysis of acute outbreaks of disease, the proportion of persons exposed to the disease during the outbreak who do become ill.
(ә-tak´) an episode or onset of illness. anxiety attack panic attack. heart attack popular term for myocardial infarction. any of various types of acute episodes of ischemic heart disease. panic attack ...
small regions of increased density along the sarcolemma of skeletal muscles to which myofilaments seem to attach; cf. dense bodies, under body.
Agency for Toxic Substances and Disease Registry, an agency of the United States Department of Health and Human Services.
(ә-tach´mәnt) the initial stage of infection of a cell by a virus, in which the viral envelope finds a suitable receptor on the cell surface, enabling the virus to enter. Called also adsorption.
American Thoracic Society.
severe toxic reaction due to overdosage of atropine. Symptoms include dryness of mouth, thirst, difficulty in swallowing, dilated pupils, tachycardia, fever, delirium, stupor, and a rash on the face, neck, and upper trunk.
(at″ro-pin´ik) having actions similar to those of atropine; that is, antagonizing the muscarinic effects of acetylcholine.
atrophy of aging
atrophy of disuse
(at´ro-pēn) an anticholinergic alkaloid found in belladonna; it acts as a competitive antagonist of acetylcholine at muscarinic receptors, blocking stimulation of muscles and glands by parasympathetic and cholinergic sympathetic nerves; used as the sulfate salt as a smooth muscle relaxant, as an antiarrhythmic, as ...
(at″ro-fo-dur´mә) atrophy of the skin.
(at´rә-fe) decrease in size of a normally developed organ or tissue; see also wasting. to undergo or cause such a decrease. adj., atroph´ic., adj.
vaginitis occurring in postmenopausal women, associated with estrogen deficiency. The two most common types are senile vulvovaginitis and adhesive vaginitis.
a type of autoimmune thyroiditis with atrophy of the follicles and without goiter.
a chronic form of nonallergic noninfectious rhinitis marked by wasting of the mucous membrane and the glands. It is sometimes the result of trauma, vascular damage by radiation therapy, and environmental irritants, and disease has also been implicated.
chronic gastritis with atrophy of the mucous membranes and glands.
a type of chronic pharyngitis involving wasting of the submucous tissue, dryness, and thick secretions. Called also pharyngitis sicca.
a spontaneous fracture resulting from atrophy of the bone.
a type in which the liver is decreased in size; it may be seen in the alcoholic, but is more common in posthepatic or postnecrotic cirrhosis.
acne vulgaris in which, after the small papular lesions disappear, tiny atrophic pits and scars remain.
oral candidiasis marked by erythematous, pebbled patches on the hard or soft palate, buccal mucosa, and dorsal surface of the tongue, a complication of numerous different conditions such as vitamin deficiency, diabetes mellitus, or poorly fitting dentures. There are acute forms and a chronic form called denture stomatitis...
(at´ro-mid) trademark for a preparation of clofibrate, used in treatment of hyperlipoproteinemia.
(ә-tro´fe-ә) Latin word meaning atrophy.
(a´tre-әm) pl. a´tria a chamber affording entrance, especially one of the upper chambers on either side of the heart, which receive blood from the body and transmit it to the ventricles. Atria of the heart. left atrium the upper chamber of...
AV conduction the normal conduction of atrial impulses in the heart, passing through the atrioventricular node and the His-Purkinje system to the ventricles.
the part of the membranous portion of the interventricular septum between the left ventricle and the right atrium.
cardiac valves that connect an atrium and a ventricle. The right atrioventricular valve is the tricuspid valve and the left atrioventricular valve is the mitral valve.
atrioventricular junctional rhythm
a junctional rhythm originating in the bundle of His, with a heart rate of 40 to 60 beats per minute; called also nodal rhythm.
atrioventricular (AV) nodal reentry
an arrhythmia-causing mechanism in which two opposing pathways are established within the atrioventricular node (longitudinal dissociation); the anterograde pathway, which is usually slower, activates the ventricles and the retrograde pathway, which is usually faster, activaties the atria. This mechanism is responsible fo...
AV node a collection of cardiac fibers at the base of the interatrial septum that transmits the cardiac impulse initiated by the sinoatrial node.
in the conduction system of the heart, the junction between the atrioventricular node and the nonbranching portion of the bundle of His.
the transverse groove marking off the atria of the heart from the ventricles.
AV interval P–R interval. in dual chamber pacing, the length of time between the sensed or paced atrial event and the next sensed or paced ventricular event, measured in milliseconds; called also atrioventricular or AV delay.
bundle of His.
an ectopic beat arising prematurely in the atrioventricular junction and traveling toward both the atria and ventricles. If unimpeded, it causes the P wave to be premature and abnormal or absent and the QRS complex to be premature. Called also junctional extrasystole.
any interruption of the conduction of electrical impulses from the atria to the ventricles; it can occur at the level of the atria, the atrioventricular node, the bundle of His, or the Purkinje system. See also heart block. a type of heart block in which the blocking is at the atrioventricular junction. It is call...
atrioventricular sequential time
a fixed nonprogrammable interval that extends from the atrial stimulus to the ventricular stimulus.
atrioventricular (AV) nodal reentrant tachycardia
that resulting from reentry in or around the atrioventricular node, characterized by a QRS complex of supraventricular origin, sudden onset and termination, and a regular rhythm at a rate of 150 to 250 beats per minute. See also antidromic atrioventricular (AV) reciprocating tachycardia and orthodromic atrioventricular (AV) rec...
atrioventricular (AV) reciprocating tachycardia
(AVRT) a reentrant tachycardia in which the reentrant circuit contains both the normal pathway through the AV node and the His bundle and an accessory pathway as integral parts. See also antidromic atrioventricular reciprocating tachycardia and orthodromic atrioventricular reciprocating tachycardia.
atrioventricular junctional pacemaker
an ectopic pacemaker found in the atrioventricular junction.
atrioventricular sequential pacemaker
an artificial cardiac pacemaker used in patients with abnormal sinus node function and impaired atrioventricular conduction; it senses ventricular, and sometimes atrial, activity and in addition to stimulating the atrium also stimulates the ventricle after an appropriate delay. Committed versions invariably deliver the ve...
the common canal connecting the primordial atrium and ventricle; it sometimes persists as a congenital anomaly.
atrioventricular junctional premature complex
(a″tre-o-ven-trik″u-la´ris kә-mu´nis) a congenital cardiac anomaly in which the endocardial cushions fail to fuse, the ostium primum persists, the atrioventricular canal is undivided, a single atrioventricular valve has anterior and posterior cusps, and there is a defect of the membranous interve...
atrioventricular nodal artery
a branch of the right coronary artery usually arising opposite the origin of the posterior interventricular artery and inserting into the atrioventricular node.
(a″tre-o-ven-trik´u-lәr) pertaining to or connecting an atrium and ventricle of the heart.
(a″tre-o-sep´to-pek″se) surgical correction of a defect in the interatrial septum.
(a″tre-o-sep´to-plas″te) repair of the interatrial septum.
atrial venous pulse.
rise in arterial blood pressure (vasoconstriction) attributed to a change of pressure in the right atrium and great veins.
(a″tre-o-meg´ә-le) abnormal enlargement of an atrium of the heart.
(a″tre-o-pep´tin) a peptide hormone that promotes the loss of fluid and electrolytes and the reduction of vascular tone.
atrial venous pulse
a venous pulse in the neck that has an accentuated a wave during atrial systole, because of increased force of contraction of the right atrium; this is characteristic of tricuspid stenosis.
tachycardia originating from an atrial locus, usually having between 160 and 190 beats per minute, with no participation by the atrioventricular node or the sinoatrial node. It is recognizable on the electrocardiogram because the P wave precedes the QRS complex, as opposed to being merged with it or following it. This con...
atrial synchronous ventricular inhibited pacemaker
a dual chamber pacemaker similar to an atrial synchronous ventricular one but able to sense ventricular as well as atrial activity. Called also VDD pacemaker.
atrial synchronous ventricular pacemaker
a dual chamber pacemaker that senses atrial activity and delivers a ventricular stimulus after a preset interval; used in patients with impaired atrioventricular conduction but normal sinus node function. Called also VAT pacemaker. See also atrial synchronous ventricular inhibited pacemaker.
atrial septal defect
a congenital heart defect in which the ostium primum or ostium secundum (openings in the septum primum of the embryonic heart) fails to close completely after birth. When an opening remains between the atria, some of the oxygen-rich blood from the left atrium passes into the right atrium and travels back to the lungs with...
atrial pressure waves
the three elevations commonly seen on the graphic representation of the cardiac cycle, known as the a wave, c wave, and v wave.
reentry in which the entire reentrant circuit lies within one or both atria, excluding the sinus node.
atrial pacing stress test
a stress test in which temporary immediately reversible atrial pacing is used to stress coronary reserve; used for patients incapable of exercise or in whom an exercise stress test is contraindicated.
atrial natriuretic factor
(ANF) a hormone produced in the cardiac atrium; an inhibitor of renin secretion and thus of the production of angiotensin, and a stimulator of aldosterone release. Its effect is increased excretion of water and sodium and a lowering of blood pressure.
one in which the stimulus is thought to arise in the atrium elsewhere than at the sinoatrial node.
a cardiac arrhythmia in which the atrial contractions are rapid (230–380 per minute), but regular. Two types, I and II, are distinguished according to rate; Type I is also more amenable to cardioversion. In Type I the atrial rate is usually 290 to 310 per minute but can range from 230 to 350. In Type II the atrial rate is...
atrial demand triggered pacemaker
an artificial cardiac pacemaker that delivers stimuli to the atrium at a fixed rate in the absence of sensed atrial activity; spontaneous cardiac activity triggers pacemaker output, which falls ineffectively in the myocardial refractory period and initiates a new pacemaker stimulation cycle. Called also AAT pacemaker.
the P wave of the electrocardiogram, representing electrical activity of the atria. See also ventricular complex.
atrial demand inhibited pacemaker
an artificial cardiac pacemaker that delivers stimuli to the atrium at a fixed rate in the absence of sensed atrial activity; spontaneous cardiac activity causes inhibition of pacemaker output, termination of the current stimulation cycle, and initiation of a new cycle. Called also AAI pacemaker.
an ectopic beat originating in an atrium.
(a´tre-әl) pertaining to an atrium.
atrial asynchronous pacemaker
an artificial cardiac pacemaker that stimulates the atrium at a constant rate, without sensing atrial or ventricular activity; now rarely used except to initiate or terminate some tachycardias. Called also AOO pacemaker.
atretic ovarian follicle
an involuted ovarian follicle.
(a´tre-ә) plural of atrium.
a suture fused into the end of a small eyeless needle.
(ә-tre´zhә) congenital absence or closure of a normal body opening or tubular structure; see also obstruction. adj., atret´ic., adj. atresia ani imperforate anus. atresia folliculi follicular atresia.
(a″traw-mat´ik) not producing injury or damage.
an eyeless surgical needle with the suture attached to a hollow end.
(at″rә-kūr´e-әm) a neuromuscular blocking agent of intermediate duration; used as the besylate salt for intravenous administration as an adjunct to anesthesia to induce skeletal muscle relaxation during surgery and facilitate mechanical ventilation.
ambient temperature and pressure, saturated; denoting a volume of gas saturated with water vapor at ambient temperature and barometric pressure.
(a-tok´sik) not poisonous; not due to a poison.
(a-te-pe´ās) adenosinetriphosphatase. Na+,K+-ATPase an enzyme that spans the plasma membrane and hydrolyzes adenosine triphosphate to provide the energy necessary to drive the cellular sodium pump.
(ә-to´vә-kwōn″) an antibiotic used in treatment of mild to moderate pneumocystis pneumonia and the prevention and treatment of falciparum malaria; administered orally.
(ә-tor´vә-stat″in) an agent that inhibits cholesterol synthesis, used as the calcium salt in treatment of primary hypercholesterolemia and hyperlipidemia; administered orally.
(at´ә-pe) a clinical hypersensitivity state or allergy with a hereditary predisposition; the tendency to develop an allergy is inherited, although the specific clinical form (such as hay fever or asthma) is not. The antibody reagin is involved. Called also atopic, hereditary, or spontaneous allergy
a type seen in persons with longstanding atopic dermatitis, often in the second to third decade of life.
atopic eczema a chronic inflammatory skin disorder seen in persons with a hereditary susceptibility to develop itching (pruritus); it is often accompanied by allergic rhinitis, hay fever, or asthma. The extreme itchiness leads to scratching and rubbing that in turn results in the typical lesions of eczema.
(a-top´ik) (ә-top´ik) displaced; ectopic. pertaining to atopy.
(at´ә-ne) lack of normal tone or strength; flaccidity. adj., aton´ic., adj.
(at´ә-pen) the antigen responsible for atopy.
an absence seizure characterized by sudden loss of muscle tone.
atonic neurogenic bladder
neurogenic bladder due to destruction of sensory nerve fibers from the bladder to the spinal cord, marked by absence of control of bladder functions and of desire to urinate, bladder overdistention, and an abnormal amount of residual urine; it is usually associated with tabes dorsalis or pernicious anemia but may be seen ...
(ә-to´ne-ә) Latin word meaning atony.
neurogenic bladder in which the bladder is dilated and poorly contracting and the lesion is not in the central nervous system.
(Z) a number expressive of the number of protons in an atomic nucleus, or the positive charge of the nucleus expressed in terms of the electronic charge.
the sum of the masses of the constituents of an atom, expressed in atomic mass units (or daltons), in SI units (i.e., kilograms), or as a dimensionless ratio derived by comparing the mass to the mass of an atom of carbon-12, which is taken as 12.000. Abbreviated at wt.
atomic mass unit
(u) (amu) the unit of mass equal to 1/12 the mass of the nuclide of carbon 12. Called also dalton.
nucleus (def. 4).
(at´әm) the smallest particle of an element that has all the properties of the element. adj., atom´ic., adj. There are two main parts of an atom: the nucleus and the electron cloud. The nucleus is made up of protons, which carry a positive electrical charge, and (except in hydrogen) neutrons, which contain one ...
the pressure exerted by the atmosphere, usually considered as the downward pressure of air onto a unit of area of the earth's surface; the unit of pressure at sea level is one atmosphere. Pressure decreases with increasing altitude.
(a-to´shә) sterility in the female.
atmosphere (def. 3).
(at´mәs-fēr) the entire gaseous envelope surrounding the earth and subject to the earth's gravitational field. the air or climate in a particular place. adj., atmospher´ic. a unit of pressure, being that exerted by the earth's atmosphere at sea level; equal to 1.01325 × 105pascals (appro...
(at″lo-ak´soid) pertaining to the atlas and axis.
(at´lәs) the first cervical vertebra, the uppermost bone of the vertebral column, which supports the skull. Atlas. (A), (Top) seen from above; (bottom) seen from the side. (B), Position of the atlas (red), between the occipital bone and the axis.
(at-lan´tәl) pertaining to the atlas.
either of two joints, each formed by a superior articular pit of the atlas and a condyle of the occipital bone.
(ә-thi´re-ә) absence of functioning thyroid tissue. hypothyroidism.
(at´ĭ-van) trademark for preparations of lorazepam, an antianxiety agent, sedative, and anticonvulsant.
(ә-thīm´e-ә) absence of functioning thymus tissue. lack of feeling and emotion, as found in depression and other mental disorders.
(ә-threp´se-ә) extreme malnutrition and wasting of subcutaneous tissue and muscle; see also marasmus. adj., athrep´tic., adj.
a constitutional type marked by broad shoulders, deep chest, flat abdomen, thick neck, and good muscular development.
(ath″ә-to´sis) repetitive involuntary, slow, sinuous, writhing movements. Positions of fingers in movements of athetosis.
(ath´lēts) a fungal infection of the skin of the foot, causing itching and often blisters and cracks, usually between the toes. Causative agents are Candida albicans, Epidermophyton floccosum, and species of Trichophyton, which thrive in warmth and dampness. Called also tinea pedis.
(ath´ә-toid) resembling athetosis. affected with athetosis.
(ath″әr-o-sklә-ro´sis) a common form of arteriosclerosis in which deposits of yellowing plaques (atheromas) containing cholesterol, other lipoid material, and lipophages are formed on the inner walls of large and medium-sized arteries. adj., atherosclerot´ic., adj.
loss of intima over an atheroma, often causing thrombus formation.
(ath″әr-o´mә) an abnormal mass of fatty or lipid material with a fibrous covering, existing as a discrete, raised plaque within the intima of an artery. adj., atherom´atous., adj.
(ath″әr-o″mә-to´sis) the presence of multiple atheromas.
(ath″әr-o-jen´ә-sis) formation of abnormal fatty or lipid masses in arterial walls. adj., atherogen´ic., adj.
(ә-thur″mo-sis-tal´tik) not contracting under the action of cold or heat; said of muscles.
(ath″әr-o-em´bo-lәs) pl. atheroem´boli an embolus composed of cholesterol or its esters, or of fragments of atheromatous plaques, typically lodging in small arteries.
(a-thur´mik) without rise of temperature.
a catheter containing a rotating cutter and a collecting chamber for debris, used for atherectomy and endarterectomy; it is inserted percutaneously under radiographic guidance.
(ath″әr-ek´tә-me) the removal of atherosclerotic plaque from an artery using a rotary cutter inside a special catheter guided radiographically; it does not extend to the tunica intima as endarterectomy does.
(ә-the´le-ә) congenital absence of the nipples.
(at″ә-lo-mi-e´le-ә) imperfect development of the spinal cord.
(ә-ten´ә-lol) a cardioselective beta-adrenergic blocking agent used in the treatment of hypertension and chronic angina pectoris and the prevention and treatment of myocardial infarction and cardiac arrhythmias; administered orally or intravenously.
(at″ә-lo-kahr´de-ә) imperfect development of the heart.
(at″ә-lo-sef´ә-le) imperfect development of the skull. adj., atelocephal´ic, ateloceph´alous., adj.
atelectatic otitis media
tympanic membrane atelectasis.
(ә-te´le-ә) imperfect or incomplete development.
(at″ә-lek´tә-sis) a collapsed or airless state of the lung, which may be acute or chronic and involving all or only part of a lung. The primary cause is obstruction of the bronchus that serves the affected area. When atelectasis occurs suddenly or acutely, there may be dyspnea, cyanosis, fever, a drop in blo...
(at″ә-zan´ә-vir) an in inibitor of human immunodeficiency virus-1 (HIV-1) protease, used as the sulfate salt in the treatment of HIV-1 infection.
an unsteady, uncoordinated walk, with a wide base and the feet thrown out, coming down first on the heel and then on the toes with a double tap.
(ә-tak″se-ә-fa´zhә) inability to arrange words into sentences.
a severe, autosomal recessive, progressive ataxia, associated with telangiectasias (dilation of small blood vessels) in the skin and eyes; immunodeficiency with frequent infections of the respiratory tract from sinuses to lungs; and abnormal eye movements. Called also Louis-Bar syndrome.
(ә-tak´se-ә) failure of muscular coordination; irregularity of muscular action. adj., atac´tic, atax´ic., adj.
(at´ә-raks) trademark for preparations of hydroxyzine hydrochloride, an antianxiety agent, antiemetic, sedative, and antipruritic.
(at″ә-rak´se-ә) serenity, calmness, peace of mind.
(at´ә-viz-әm) apparent inheritance of characters from remote ancestors. adj., atavis´tic., adj.
(ә-tak´tik) pertaining to or characterized by ataxia; marked by incoordination or irregularity.
(at´ә-brēn) trademark for a preparation of quinacrine, an anthelmintic and antimalarial agent.
(a″sә-no´ve-ә) absence or insufficiency of synovial secretion.
(a″sin-tak´se-ә) lack of proper and orderly embryonic development.
(a-sis´to-le) cardiac standstill or arrest; absence of heartbeat. adj., asystol´ic., adj.
(a″sin-ur´je-ә) lack of coordination among parts or organs normally acting in unison. adj., asyner´gic., adj.
(a″sin-ek´e-ә) absence of continuity of structure.
(ә-sin´dә-sis) a pattern of language in which words and phrases are juxtaposed without grammatical linkage; seen in schizophrenic and other mental disorders.
(ә-sin´klĭ-tiz-әm) oblique presentation of the fetal head in labor, called anterior asynclitism when the anterior parietal bone is designated the point of presentation, and posterior asynclitism when the posterior parietal bone is so designated. dyserythropoiesis.
(a-sing´krә-ne) the occurrence at distinct times of events normally synchronous; disturbance of coordination; called also asynchronism. adj., asyn´chronous., adj.
asynchronous ventricular pacemaker
ventricular asynchronous pacemaker.
a pacing mode which there is regular stimulation without regard to sensed cardiac signals.
an implanted pacemaker that delivers stimuli at a fixed rate, independent of any atrial or ventricular activity; this type is now rarely used except to initiate or terminate some tachycardias.
(a-sing´krә-nәs) pertaining to asynchronism. in cardiac pacing terminology, said of a pacemaker that cannot sense any spontaneous underlying cardiac electrical activity, so that pacing is done at a fixed, constant rate.
asynchronous atrial pacemaker
atrial asynchronous pacemaker.
(ә-sim´fә-tәs) separate or distinct; not grown together.
(a″simp-to-mat´ik) showing no symptoms or signs of a disease or disorder.
(a-sim´ә-tre) lack or absence of symmetry; dissimilarity in corresponding parts or organs on opposite sides of the body that are normally alike. In chemistry, lack of symmetry in the special arrangements of the atoms and radicals within the molecule or crystal. adj., asymmet´rical., adj.
(ă-sim-bo´le-ә) loss of ability to understand symbols, such as words, figures, gestures, signs; called also asemasia.
asymmetrical septal hypertrophy
hypertrophic cardiomyopathy. the term is sometimes limited to cases of hypertrophic cardiomyopathy in which the hypertrophy is localized to the interventricular septum. See also hypertrophic obstructive cardiomyopathy.
a family of RNA viruses that cause gastroenteritis in humans and other animals; the single genus is Astrovirus.
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