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Look up: proteasome

  1. Proteasome
    Proteasome: A protein degradation 'machine' within the cell that can digest a variety of proteins into short polypeptides and amino acids. The proteasome is itself made up of proteins. It requires ATP to work. It is hollow and has openings at both ends to allow entry of the protein to be digested. A...
    Found on http://www.medterms.com/script/main/art.

  2. proteasome
    <cell biology> Proteolytic complexes that degrade cytosolic and nuclear proteins. Implicated in ATP dependent ubiquitin protein complex degradation and in antigen processing in antigen presenting cells. The 20S proteasome (700 kD), essential in ATP ubiquitin degradation pathway, has 13-15 subu...
    Found on http://www.mondofacto.com/facts/dictiona

  3. proteasome
    (from the article `Ciechanover, Aaron J.`) ...to a protein targeted for destruction and accompanies it to a proteasome—essentially a sac of powerful enzymes that break the protein into its ... ...meaning `everywhere,` because it occurs in so many different cells and organisms) attaches itself to the protein targeted for d...
    Found on http://www.britannica.com/eb/a-z/p/122

  4. proteasome
    Type: Term Pronunciation: prō′tē-ă-sōm Definitions: 1. Cytoplasmic organelle, composed of a cylindric core particle bound by two regulatory particles at each end, responsible for degrading endogenous proteins. Proteins to be destroyed are recognized by proteasomes because o...
    Found on http://www.medilexicon.com/medicaldictio

  5. Proteasome
    `Proteasomes` are very large protein complexes inside all eukaryotes and archaea, and in some bacteria. In eukaryotes, they are located in the nucleus and the url=http://www.jbc.org/cgi/pmidlookup?view=long&pmid=8125997-->--> The main function of the proteasome is to degrade unneeded or damaged ...
    Found on http://en.wikipedia.org/wiki/Proteasome

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13 February 2012

This day in history:
The fifth queen of Henry VIII was Catherine Howard. Her father was very poor, and Catherine lived mainly with Agnes, widow of the 2nd duke of Norfolk. Henry was evidently charmed by her and he was privately married to Catherine at Oatlands in July 1540. In November 1541 Archbishop Thomas Cranmer informed Henry that his queen's past life had not been stainless. After some denials the queen herself admitted that this was true; but denied that she had misconducted herself since her marriage. Some fresh information, however, very soon came to light showing that she had been unchaste since her marriage; a bill of attainder was passed through parliament, and on the 13th of February 1542 the queen was beheaded. read more

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