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Look up: p53

  1. p53
    A tumour supressor gene that, when working normally, helps to stop cells becoming cancerous. The p53 gene has been found to be damaged in most human cancers.
    Found on http://www.cancerhelp.org.uk/glossary.as

  2. p53
    p53: A tumor suppressor. The designation 'p53' stands for 'protein 53 kilodaltons' in size. p53 is a specific protein produced by a gene that functions to suppress the growth of tumors. The p53 gene is the most commonly mutated gene known in human cancer. Like other tumor-suppressor genes, p53 norma...
    Found on http://www.medterms.com/script/main/art.

  3. p53
    A 393 residue (in humans) phosphoprotein that is a common tumour antigen, expressed in many transformed cells. However, it is believed to be the product of a tumour suppressor gene, rather than an oncogene, as it is frequently inactivated or mutated in tumours. See Table O1.
    Found on http://www.encyclo.co.uk/visitor-contrib

  4. p53
    <molecular biology, oncogene> A gene which encodes a protein that regulates cell growth and is able to cause potentially cancerous cells to destroy themselves. ... In humans it is a 393 residue phosphoprotein that is a tumour suppressor gene rather than an oncogene, as it is frequently inactiv...
    Found on http://www.mondofacto.com/facts/dictiona

  5. p53
    (from the article `tumour suppressor gene`) ...Subsequent research revealed that mutations in this gene also play a role in cancers of the bone, lung, breast, cervix, prostate, and bladder. A ... The p53 protein was discovered in 1979. It resides in the nucleus, where it regulates cell proliferation and cell death. In particular, it pre...
    Found on http://www.britannica.com/eb/a-z/p/1

  6. p53
    Type: Term Definitions: 1. A tumor suppressor gene located on the short arm of chromosome 17 that encodes a nucleophosphoprotein that binds DNA and negatively regulates cell division; frequently measured as a marker of malignant diseases.
    Found on http://www.medilexicon.com/medicaldictio

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12 February 2012

This day in history:
/calendar/ On February 12, 1809, Charles Robert Darwin was born at The Mount in Shrewsbury, Shropshire, England. Darwin was one of the last of the eclectic scientists who preceded the age of professional specialization. His genius lay in his ability to select, from the facts which he so diligently collected, every relevant point and fit it into his bold and far-reaching theories. He was not the first to advance a theory of evolution; but his massive weight of evidence carried conviction where earlier theorists had failed. He was shy and modest and shrank from controversy, an unfortunate trait in the author of the most controversial book of the century. read more

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