Simian crease: A single transverse palmar crease, a minor variation associated with Down syndrome (trisomy 21). Also called a four-finger crease, single palmar flexion crease, single upper palm crease, or line. There are most often two transverse palmar creases, a proximal one and a more distal one, neither of which extends all the way across the p
Found on http://www.medterms.com/script/main/art.asp?articlekey=40405
A single palmar crease associated with Down's syndrome. ... (27 Sep 1997) ...
Found on http://www.mondofacto.com/facts/dictionary?simian+crease
Type: Term Definitions: 1. a single transverse palmar crease formed by fusion of the proximal and distal palmar creases, so called because of its similarity to the transverse flexion crease seen in some monkeys; a common but not pathognomonic feature of Down syndrome; also found in 1% of the normal population.
Found on http://www.medilexicon.com/medicaldictionary.php?t=21157
A major crease across the entire palm of the hand that is frequently seen in individual's with Down syndrome.
Found on http://www.pregnology.com/AZ/S/3
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