Brown pigment characteristic of ageing. Found in lysosomes and is the product of peroxidation of unsaturated fatty acids and symptomatic, perhaps, of membrane damage rather than being deleterious in its own right.
Found op http://www.encyclo.co.uk/visitor-contributions.php
<protein> Brown pigment characteristic of ageing. Found in lysosomes and is the product of peroxidation of unsaturated fatty acids and symptomatic, perhaps, of membrane damage rather than being deleterious in its own right. ... (18 Nov 1997) ...
Found op http://www.mondofacto.com/facts/dictionary?lipofuscin
(lip″o-fu´sin) a yellow to brown, granular, iron-negative lipid pigment found particularly in muscle, heart, liver, and nerve cells; it is the product of cellular wear and tear, accumulating in lysosomes with age. lipochrome.
Found op http://www.encyclo.co.uk/local/21001
(from the article `aging`) An important age change is the accumulation of pigments and inertpossibly deleteriousmaterials within and between cells. The pigment lipofuscin ... ...with advancing age. Structural changes include a gradual loss of muscle fibres with an infiltration of fat and...
Found op http://www.britannica.com/eb/a-z/l/56
Lipofuscin is the name given to finely granular yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion. It is considered one of the aging or "wear-and-tear" pigments, found in the liver, kidney, heart muscle, adrenals, nerve cells, and ganglion cells. It is speci...
Found op http://en.wikipedia.org/wiki/Lipofuscin
A pale yellow-brown pigment, made of free-radical-damaged protein and fat, which stains red with Sudan black and is PAS-positive. Lipofuscin granules accumulate in the cytoplasm of muscle and nerve cells, acting as a marker of wear and tear. They concentrate beneath the skin (forming so-called age s...
Found op http://www.daviddarling.info/encyclopedia/L/lipofuscin.html
Type: Term Pronunciation: lip′ō-fyūs′in Definitions: 1. Brown pigment granules representing lipid-containing residues of lysosomal digestion and considered one of the aging or 'wear and tear' pigments; found in liver, kidney, heart muscle, adrenal, and ganglion cells.
Found op http://www.medilexicon.com/medicaldictionary.php?t=50778
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