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Haplo-sufficiency
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Haploinsufficiency
Haploinsufficiency: A situation in which the total level of a gene product (a particular protein) produced by the cell is about half of the normal level and that is not sufficient to permit the cell to function normally. Another way to define haploinsufficiency is as a condition that arises when the... Found op http://www.medterms.com/script/main/art.html?articlekey=18474
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Haploinsufficiency
Haploinsufficiency occurs when a diploid organism only has a single functional copy of a gene (with the other copy inactivated by mutation) and the single functional copy of the gene does not produce enough of a gene product (typically a protein) to bring about a wild-type condition, leading to an ... Found op http://en.wikipedia.org/wiki/Haploinsufficiency
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haploinsufficiency
A situation in which the protein produced by a single copy of an otherwise normal gene is not sufficient to assure normal function. Found op http://www.daviddarling.info/encyclopedia/H/haploinsufficiency.html
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