Look up: Endonuclease

1. endonuclease
   Type: Term Pronunciation: en′dō-nū′klē-ās Definitions: 1. An enzyme (phosphodiesterase) that cleaves the internal phosphodiester bonds in a DNA molecule, thus producing DNA fragments of varying size.
   Found on http://www.medilexicon.com/medicaldictio
   
   
2. Endonuclease
   See Nuclease.
   Found on http://filebox.vt.edu/cals/cses/chagedor
   
   
3. endonuclease
   A nuclease which cleaves phosphodiester bonds within a nucleic acid strand.
   Found on http://ppathw3.cals.cornell.edu/glossary
   
   
4. Endonuclease
   Nucleases are enzymes that break down nucleic acids into strands of DNA. 'Endo' or inside nucleases act at points along the strand and thus break DNA into short pieces. Endonucleases recognise a particular base sequence in DNA and cut the DNA. Some endonucleases cut the DNA at a specific point while others randomly split the DNA sequences. Specific endonucleases are used by genetic engineers who excise strands of DNA coded for a desirable genetic character. Endonucleases are classed as 'Restriction enzymes' since they are employed e.g., by bacteria to restrict infection by viruses (bacteriophages). The bacterial restriction enzyme attacks the DNA of the infecting organisms.
   Found on http://www.encyclo.co.uk/visitor-contrib
   
   
5. endonuclease
   [n] - a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
   Found on http://www.webdictionary.co.uk/definitio
   
   
6. Endonuclease
   Endonuclease: An enzyme that cleaves a nucleic acid (DNA or RNA) at specific internal sites in the nucleotide base sequence.
   Found on http://www.medterms.com/script/main/art.
   
   
7. endonuclease
   One of a large group of enzymes that cleave nucleic acids at positions within the chain. Some act on both RNA and DNA (eg. S1 nuclease, EC.3.1.30.1, that is specific for single stranded molecules). Ribonucleases such as pancreatic, T1 etc. are specific for RNA, Deoxyribonucleases for DNA. Bacterial restriction endonucleases are crucial in recombinant DNA technology for their ability to cleave double-stranded DNA at highly specific sites.
   Found on http://www.encyclo.co.uk/visitor-contrib
   
   
8. endonuclease
   <enzyme> One of a large group of enzymes that cleave nucleic acids at positions within the chain. Some act on both RNA and DNA (e.g. S1 nuclease, EC.3.1.30.1, that is specific for single stranded molecules). ... Ribonucleases such as pancreatic, T1 etc. Are specific for RNA, Deoxyribonucleases...
   Found on http://www.mondofacto.com/facts/dictiona
   
   
9. endonuclease
   noun a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes
   Found on http://wordnetweb.princeton.edu/perl/web
   
   
10. endonuclease
    (en″do-noo´kle-ās) an enzyme that cleaves internal bonds of polynucleotides. restriction endonucleases enzymes that cleave large DNA molecules at specific sequences of four to six nucleotides. See also recombinant DNA technology.
    Found on http://www.encyclo.co.uk/local/21001
    
    
11. endonuclease
    (from the article `nucleic acid`) Nucleases are enzymes that hydrolytically cleave the phosphodiester backbone of DNA. Endonucleases cleave in the middle of chains, while exonucleases ...
    Found on http://www.britannica.com/eb/a-z/e/29
    
    
12. endonuclease
    An enzyme that cleaves its nucleic acid substrate at internal sites in the nucleotide sequence.
    Found on http://linkage.rockefeller.edu/wli/gloss
    
    
13. endonuclease
    A protein that recognizes specific, short nucleotide sequences and cuts DNA at those sites. Bacteria contain over 400 such enzymes that recognize and cut over 100 different DNA sequences. See restriction enzyme cutting site.
    Found on http://linkage.rockefeller.edu/wli/gloss
    
    
14. Endonuclease
    See: restriction enzyme
    Found on http://www.ornl.gov/sci/techresources/Hu
    
    
15. Endonuclease
    See: restriction enzyme
    Found on http://www.ornl.gov/sci/techresources/Hu
    
    
16. Endonuclease
    `Endonucleases` are enzymes that cleave the phosphodiester bond within a polynucleotide chain, in contrast to exonucleases, which cleave phosphodiester bonds at the end of a polynucleotide chain. Typically, a restriction site will be a palindromic sequence four to six nucleotides long. Most restrict...
    Found on http://en.wikipedia.org/wiki/Endonucleas