Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. ==Structure=
Found on http://en.wikipedia.org/wiki/Claudin
Type: Term Pronunciation: klaw′din Definitions: 1. A membrane protein, juxtaposed strands of which form tight junctions between epithelial cells.
Found on http://www.medilexicon.com/medicaldictionary.php?t=18059
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