(breast cancer gene, cancer gene, ovarian cancer gene) Gene that increases the risk of getting breast, ovarian, bowel or prostate cancer. Out of every 100 women who have a faulty version of this gene, between 80 and 85 will develop breast cancer at some point in their life. So they have a lifetime risk of 80-85%. Ovarian cancer lifetime risk is
Found on http://www.cancerhelp.org.uk/utilities/glossary/index.htm?search=b
BRCA1: A gene that normally acts to restrain the growth of cells in the breast but which, when mutated, predisposes to breast cancer. The gene's full name is breast cancer 1, early onset. The BRCA1 gene belongs to a class of genes known as tumor suppressor genes. Like other tumor suppressor genes, BRCA1 regulates the cycle of cell division by keepi
Found on http://www.medterms.com/script/main/art.asp?articlekey=2522
<molecular biology> BRCA1 is a tumour-supressing gene, if even one copy of it is damaged, cancer can develop. ... Certain mutations confer a high probability (85% lifetime risk) of developing breast cancer, and other types cause ovarian cancer. Familial mutations of this gene are particularly common among people in the Ashkenazi Jewish ethnic
Found on http://www.mondofacto.com/facts/dictionary?BRCA1
(from the article `tumour suppressor gene`) ...suppressor genes, such as p53, have been identified. The mutated form of p53 has been implicated in more than 50 percent of all cancers. Mutations ... ...cancer generally appears late in life, while the familial forms can present much earlier, often before age 40. For familial breast cancer...
Found on http://www.britannica.com/eb/a-z/b/108
A gene on chromosome 17 that normally helps to suppress cell growth. A person who inherits certain mutations (changes) in a BRCA1 gene has a higher risk of getting breast, ovarian, prostate, and other types of cancer.
Found on http://www.cancer.gov/dictionary?expand=B
(Breast Cancer1) An altered or faulty gene passed on at birth from either parent that causes a permanent change in a person
Found on http://www.breastcancercare.org.uk/breast-cancer-information/glossary
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