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Anagrelide
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anagrelide
(an-ag´rә-līd) an agent used in the form of the hydrochloride salt to reduce elevated platelet counts and the risk of thrombosis in treatment of hemorrhagic thrombocythemia; administered orally. Found op http://www.encyclo.co.uk/local/21001
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Anagrelide
==Mechanism== Anagrelide works by inhibiting the maturation of platelets from megakaryocytes. The exact mechanism of action is unclear, although it is known to be a phosphodiesterase inhibitor. It is a potent (IC50 = 36nM) inhibitor of phosphodiesterase-II.{Fact|date=December 2008} It inhibits PDE-... Found op http://en.wikipedia.org/wiki/Anagrelide
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anagrelide
A drug that is used to decrease the number of platelets in the blood in order to prevent blood clotting. Found op http://www.cancer.gov/dictionary?expand=A
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